Green Chemistry Approaches to the Synthesis of Pharmaceutical Intermediates: Minimizing Environmental Impact

Authors

  • Prof. C. N. R. Rao Jawaharlal Nehru Centre for Advanced Scientific Research (JNCASR), Bengaluru

DOI:

https://doi.org/10.36676/mdjc.v1.i1.1

Keywords:

Green chemistry, Pharmaceutical intermediates, Environmental impact, Sustainability, Renewable feedstocks

Abstract

The application of green chemistry principles in the synthesis of pharmaceutical intermediates, aiming to minimize environmental impact. Green chemistry emphasizes the design of chemical processes that reduce hazardous substances, waste generation, and energy consumption. By incorporating these principles, researchers seek to mitigate pollution, enhance sustainability, and promote eco-friendly manufacturing. Key strategies include the use of renewable feedstocks, catalysis, solvent-free and aqueous conditions, and efficient synthetic routes. Case studies demonstrate successful implementation, highlighting reduced environmental impact without compromising efficiency or product quality. Additionally, the importance of green metrics and sustainability assessments in process evaluation is discussed.

References

Alam, S. (2023). PMTRS: A Personalized Multimodal Treatment Response System Framework for Personalized Healthcare. International Journal of Applied Health Care Analytics, 8(6), 18–28. Retrieved from https://norislab.com/index.php/IJAHA/article/view/77

Anastas, Paul T., and John C. Warner. "Green Chemistry: Theory and Practice." Oxford University Press, 1998.

Anastas, Paul T., and Nicholas Eghbali. "Green Chemistry: Principles and Practice." Chemical Society Reviews, vol. 39, no. 1, 2010, pp. 301-312.

Ayyalasomayajula, Madan Mohan Tito, Sathishkumar Chintala, and Sandeep Reddy Narani. "Optimizing Textile Manufacturing with Neural Network Decision Support: An Ornstein-Uhlenbeck Reinforcement Learning Approach." Journal of Namibian Studies: History Politics Culture 35 (2023): 335-358.

Ayyalasomayajula, Madan Mohan Tito, Sathishkumar, Chintala. "Fast Parallelizable Cassava Plant Disease Detection using Ensemble Learning with Fine Tuned AmoebaNet and ResNeXt-101". Turkish Journal of Computer and Mathematics Education (TURCOMAT) 11. 3(2020): 3013–3023.Clark, James H., et al. "Green Chemistry and the Pharmaceutical Industry." Green Chemistry, vol. 1, no. 1, 1999, pp. 1-8.

Bhadani, U (2020). Hybrid Cloud: The New Generation of Indian Education Society. International Research Journal of Engineering and Technology, 7(9).

Bhadani, U (2022). Comprehensive Survey of Threats, Cyberattacks, and Enhanced Countermeasures in RFID Technology. International Journal of Innovative Research in Science, Engineering and Technology, 11(2)

Clark, James H., et al. "Towards a Green Chemical Industry." Science, vol. 297, no. 5582, 2002, pp. 807-810.

Constable, David J. C., et al. "Key Green Chemistry Research Areas—A Perspective from Pharmaceutical Manufacturers." Green Chemistry, vol. 9, no. 4, 2007, pp. 411-420.

Constable, David J. C., et al. "Towards a Sustainable Pharmaceutical Industry." Green Chemistry, vol. 7, no. 5, 2005, pp. 269-271.

Dunn, Peter J., et al. "Key Green Chemistry Research Areas from a Pharmaceutical Manufacturers' Perspective." Green Chemistry, vol. 7, no. 1, 2005, pp. 20-24.

Hasan, M. R., Shawon, R. E. R., Rahman, A., Al Mukaddim, A., Khan, M. A., Hider, M. A., & Zeeshan, M. A. F. (2024). Optimizing Sustainable Supply Chains: Integrating Environmental Concerns and Carbon Footprint Reduction through AI-Enhanced Decision-Making in the USA. Journal of Economics, Finance and Accounting Studies, 6(4), 57-71.

Kumar, V. (2018). Drug-excipient interaction and its importance in dosage form development: A review study. Innovative Research Thoughts, 4(5), 235–241. Retrieved from https://irt.shodhsagar.com/index.php/j/article/view/911

Luque, Rafael, and Juan Carlos Colmenares. "Green Chemistry and the Biorefinery Concept." Green Chemistry, vol. 15, no. 7, 2013, pp. 1717-1718.

Ms Shelly. (2017). Current Scenario of Regulatory Affairs In Pharmaceutical Education Sector -A review. Innovative Research Thoughts, 3(9), 145–154. Retrieved from https://irt.shodhsagar.com/index.php/j/article/view/246

Patel, A. (2024). Unani Medicine for Gastrointestinal Disorders: A Comparative Effectiveness Study. Indian Journal of Ayurveda & Alternative Medicines, 1(1), 8–14. https://doi.org/10.36676/ijaam.v1.i1.2

Preeti Sharma, & Dr. Manoj Sharma. (2022). STUDY ON ISOCONAZOLE PRONIOSOMAL GEL IN TREATING FUNGAL INFECTION. International Journal for Research Publication and Seminar, 13(4), 92–99. Retrieved from https://jrps.shodhsagar.com/index.php/j/article/view/289

Purohit, M. S. (2012). Resource management in the desert ecosystem of Nagaur district_ An ecological study of land _agriculture_ water and human resources (Doctoral dissertation, Maharaja Ganga Singh University).

Ravina Parihar, & Dr. Sourabh Sharma. (2024). Role of regulatory affairs in ensuring quality and safety of pharmaceutical products. Universal Research Reports, 11(2), 55–67. Retrieved from https://urr.shodhsagar.com/index.php/j/article/view/1254

Rhythm khanna, & Dr. Surya Prakash Gautam. (2016). A review paper on Targeted Drug Delivery Methods and their use. International Journal for Research Publication and Seminar, 7(2). Retrieved from https://jrps.shodhsagar.com/index.php/j/article/view/759

Shelly. (2018). Application of Lean Sigma In Pharmaceutical Industry - A Practitioners review. Universal Research Reports, 5(1), 290–299. Retrieved from https://urr.shodhsagar.com/index.php/j/article/view/525

Sunita Satapathy, Sanju Purohit, “POND DEGRADATION AND WILDLIFE PRESERVATION: A GEOGRAPHICAL ANALYSIS”, vol 6(2), pp.74-85,2024, doi: 10.33472/AFJBS.6.2.2024.74-85.

Sheldon, Roger A. "Green Chemistry and Resource Efficiency: Towards a Sustainable Pharmaceutical Industry." Green Chemistry, vol. 17, no. 2, 2015, pp. 752-768.

Thomas, John M., et al. "Applications of Green Chemistry Principles in Pharmaceutical Industry." Indian Journal of Pharmaceutical Sciences, vol. 72, no. 5, 2010, pp. 546-555.

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Published

17-09-2024

How to Cite

Rao, C. N. R. (2024). Green Chemistry Approaches to the Synthesis of Pharmaceutical Intermediates: Minimizing Environmental Impact. Modern Dynamics Journal of Chemistry (MDJC), 1(1), 1–6. https://doi.org/10.36676/mdjc.v1.i1.1

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Section

Original Research `Articles